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1

Herpes simplex virus US3 protein kinase regulates virus-induced apoptosis in olfactory and vomeronasal chemosensory neurons in vivo

Isamu Mori, Fumi Goshima, Daisuke Watanabe, Hiroyasu Ito, Naoki Koide, Tomoaki Yoshida, Beixing Liu, Yoshinobu Kimura, Takashi Yokochi, Yukihiro Nishiyama

Journal:

Microbes and Infection

Year:

2006

Language:

english

File:

PDF, 495 KB

english, 2006

2

Microarray analysis of transcriptional responses to infection by herpes simplex virus types 1 and 2 and their US3-deficient mutants

Maki Kamakura, Akihiro Nawa, Yoko Ushijima, Fumi Goshima, Yasushi Kawaguchi, Fumitaka Kikkawa, Yukihiro Nishiyama

Journal:

Microbes and Infection

Year:

2008

Language:

english

File:

PDF, 330 KB

english, 2008

3

The vomeronasal chemosensory system as a route of neuroinvasion by herpes simplex virus

Isamu Mori, Fumi Goshima, Hiroyasu Ito, Naoki Koide, Tomoaki Yoshida, Takashi Yokochi, Yoshinobu Kimura, Yukihiro Nishiyama

Journal:

Year:

2005

Language:

english

File:

PDF, 569 KB

english, 2005

4

Herpes simplex virus type 1 mutant HF10 oncolytic viral therapy for bladder cancer

Shin-ichi Kohno, Chenhong Luo, Fumi Goshima, Yukihiro Nishiyama, Tetsutaro Sata, Yoshinari Ono

Journal:

Year:

2005

Language:

english

File:

PDF, 368 KB

english, 2005

5

Initial Characterization of the Epstein–Barr Virus BSRF1 Gene Product

Yanagi, Yusuke, Masud, H., Watanabe, Takahiro, Sato, Yoshitaka, Goshima, Fumi, Kimura, Hiroshi, Murata, Takayuki

Journal:

Year:

2019

Language:

english

File:

PDF, 3.41 MB

english, 2019

6

Replication-competent, oncolytic herpes simplex virus type 1 mutants induce a bystander effect following ganciclovir treatment

Chenhong Luo, Isamu Mori, Fumi Goshima, Yoko Ushijima, Akihiro Nawa, Hiroshi Kimura, Yukihiro Nishiyama

Journal:

The Journal of Gene Medicine

Year:

2007

Language:

english

File:

PDF, 993 KB

english, 2007

7

Human herpesvirus 6 infection of human epidermal cell line: Pathogenesis of skin manifestations

Dr. Tetsushi Yoshikawa, Fumi Goshima, Shiho Akimoto, Takao Ozaki, Takuya Iwasaki, Takeshi Kurata, Yoshizo Asano, Yukihiro Nishiyama

Journal:

Journal of Medical Virology

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

8

Latent infection of human herpesvirus 6 in astrocytoma cell line and alteration of cytokine synthesis

Tetsushi Yoshikawa, Yoshizo Asano, Shiho Akimoto, Takao Ozaki, Takuya Iwasaki, Takeshi Kurata, Fumi Goshima, Yukihiro Nishiyama

Journal:

Journal of Medical Virology

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

9

Oncolytic viral therapy for breast cancer with herpes simplex virus type 1 mutant HF 10

Osamu Teshigahara, Fumi Goshima, Kazumasa Takao, Shin-ichi Kohno, Hideto Kimata, Akimasa Nakao, Yukihiro Nishiyama

Journal:

Journal of Surgical Oncology

Year:

2004

Language:

english

File:

PDF, 103 KB

english, 2004

10

Determination and analysis of the DNA sequence of highly attenuated herpes simplex virus type 1 mutant HF10, a potential oncolytic virus

Yoko Ushijima, Chenhong Luo, Fumi Goshima, Yohei Yamauchi, Hiroshi Kimura, Yukihiro Nishiyama

Journal:

Microbes and Infection

Year:

2007

Language:

english

File:

PDF, 382 KB

english, 2007

11

Herpes simplex virus type 2 US3 blocks apoptosis induced by sorbitol treatment

Takayuki Murata, Fumi Goshima, Yohei Yamauchi, Tetsuo Koshizuka, Hiroki Takakuwa, Yukihiro Nishiyama

Journal:

Microbes and Infection

Year:

2002

Language:

english

File:

PDF, 309 KB

english, 2002

12

Antiapoptotic activity of herpes simplex virus type 2: the role of US3 protein kinase gene

So Hata, A.Hajime Koyama, Hiroshi Shiota, Akio Adachi, Fumi Goshima, Yukihiro Nishiyama

Journal:

Microbes and Infection

Year:

1999

Language:

english

File:

PDF, 1.16 MB

english, 1999

13

Expression of herpes simplex virus type 2 US3 affects the Cdc42/Rac pathway and attenuates c-Jun N-terminal kinase activation

Takayuki Murata, Fumi Goshima, Tohru Daikoku, Hiroki Takakuwa, Yukihiro Nishiyama

Journal:

Year:

2000

Language:

english

File:

PDF, 523 KB

english, 2000

14

Herpes simplex virus encodes a virion-associated protein which promotes long cellular processes in over-expressing cells

Hiroki Takakuwa, Fumi Goshima, Tetsuo Koshizuka, Takayuki Murata, Tohru Daikoku, Yukihiro Nishiyama

Journal:

Year:

2001

Language:

english

File:

PDF, 3.05 MB

english, 2001

15

Apoptosis induction after herpes simplex virus infection differs according to cell type in vivo

Shinichi Esaki, Fumi Goshima, Sachiyo Katsumi, Daisuke Watanabe, Noriyuki Ozaki, Shingo Murakami, Yukihiro Nishiyama

Journal:

Archives of Virology

Year:

2010

Language:

english

File:

PDF, 1.16 MB

english, 2010

16

Association of Two Membrane Proteins Encoded by Herpes Simplex Virus Type 2, UL11 and UL56

Tetsuo Koshizuka, Yasushi Kawaguchi, Fumi Goshima, Isamu Mori, Yukihiro Nishiyama

Journal:

Year:

2006

Language:

english

File:

PDF, 464 KB

english, 2006

17

Intercellular trafficking and cytotoxicity of recombinant HSV-1 thymidine kinase fused with HSV-2 US11 RXP repeat peptide

Chenhong Luo, Akihiro Nawa, Youhei Yamauchi, Shinichi Kohno, Youko Ushijima, Fumi Goshima, Fumitaka Kikkawa, Yukihiro Nishiyama

Journal:

Year:

2007

Language:

english

File:

PDF, 480 KB

english, 2007

18

HF10, an attenuated herpes simplex virus (HSV) type 1 clone, lacks neuroinvasiveness and protects mice against lethal challenge with HSV types 1 and 2

Isamu Mori, Beixing Liu, Fumi Goshima, Hiroyasu Ito, Naoki Koide, Tomoaki Yoshida, Takashi Yokochi, Yoshinobu Kimura, Yukihiro Nishiyama

Journal:

Microbes and Infection

Year:

2005

Language:

english

File:

PDF, 881 KB

english, 2005

19

Identification and Characterization of the UL24 Gene Product of Herpes Simplex Virus Type 2

Zhu Hong-Yan, Takayuki Murata, Fumi Goshima, Hiroki Takakuwa, Tetsuo Koshizuka, Yohei Yamauchi, Yukihiro Nishiyama

Journal:

Year:

2001

Language:

english

File:

PDF, 266 KB

english, 2001

20

Identification and Characterization of theUL7Gene Product of Herpes Simplex Virus Type 2

Naoki Nozawa, Tohru Daikoku, Yohei Yamauchi, Hiroki Takakuwa, Fumi Goshima, Tetsushi Yoshikawa, Yukihiro Nishiyama

Journal:

Year:

2002

Language:

english

File:

PDF, 662 KB

english, 2002

21

Pilot Study of Oncolytic Viral Therapy Using Mutant Herpes Simplex Virus (HF10) Against Recurrent Metastatic Breast Cancer

Hideto Kimata, Tsuneo Imai, Toyone Kikumori, Osamu Teshigahara, Tetsuro Nagasaka, Fumi Goshima, Yukihiro Nishiyama, Akimasa Nakao

Journal:

Annals of Surgical Oncology

Year:

2006

Language:

english

File:

PDF, 205 KB

english, 2006

22

A Protective Role of Interleukin-15 in a Mouse Model for Systemic Infection with Herpes Simplex Virus

Hironaka Tsunobuchi, Hitoshi Nishimura, Fumi Goshima, Tohru Daikoku, Haruhiko Suzuki, Izumi Nakashima, Yukihiro Nishiyama, Yasunobu Yoshikai

Journal:

Year:

2000

Language:

english

File:

PDF, 227 KB

english, 2000

23

Axonal injury in experimental herpes simplex encephalitis

Isamu Mori, Fumi Goshima, Terukazu Mizuno, Yoshinori Imai, Shinichi Kohsaka, Hiroyasu Ito, Naoki Koide, Tomoaki Yoshida, Takashi Yokochi, Yoshinobu Kimura, Yukihiro Nishiyama

Journal:

Year:

2005

Language:

english

File:

PDF, 247 KB

english, 2005

24

Oncolytic viral therapy for human ovarian cancer using a novel replication-competent herpes simplex virus type I mutant in a mouse model

Akihiro Nawa, Naoki Nozawa, Fumi Goshima, Tetsuo Nagasaka, Fumitaka Kikkawa, Yoshimitsu Niwa, Toru Nakanishi, Kazuo Kuzuya, Yukihiro Nishiyama

Journal:

Gynecologic Oncology

Year:

2003

Language:

english

File:

PDF, 388 KB

english, 2003

25

Enhanced antitumoral activity of oncolytic herpes simplex virus with gemcitabine using colorectal tumor models

Shinichi Esaki, Fumi Goshima, Hiroshi Kimura, Shingo Murakami, Yukihiro Nishiyama

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 977 KB

english, 2012

26

Characterization of a Novel Ras-Binding Protein Ce-FLI-1 Comprising Leucine-Rich Repeats and Gelsolin-like Domains

Masahiro Goshima, Ken-ichi Kariya, Yuriko Yamawaki-Kataoka, Tomoyo Okada, Mitsushige Shibatohge, Fumi Shima, Etsuko Fujimoto, Tohru Kataoka

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 193 KB

english, 1999

27

Identification of Nuclear Export Signal in UL37 Protein of Herpes Simplex Virus Type 2

Daisuke Watanabe, Yoko Ushijima, Fumi Goshima, Hiroki Takakuwa, Yasushi Tomita, Yukihiro Nishiyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 228 KB

english, 2000

28

The US11 Gene Product of Herpes Simplex Virus Has Intercellular Trafficking Activity

Tetsuo Koshizuka, Hiroki Takakuwa, Fumi Goshima, Takayuki Murata, Yukihiro Nishiyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 235 KB

english, 2001

29

Enhanced cytotoxicity with a novel system combining the paclitaxel-2′-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus

Daisuke Ishida, Akihiro Nawa, Tadatoshi Tanino, Fumi Goshima, Chen Hong Luo, Masahiro Iwaki, Hiroaki Kajiyama, Kiyosumi Shibata, Eiko Yamamoto, Kazuhiko Ino, Tatsuya Tsurumi, Yukihiro Nishiyama, Fumit

Journal:

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

30

Iba1-expressing microglia respond to herpes simplex virus infection in the mouse trigeminal ganglion

Isamu Mori, Fumi Goshima, Tetsuo Koshizuka, Yoshinori Imai, Shinichi Kohsaka, Naoki Koide, Tsuyoshi Sugiyama, Tomoaki Yoshida, Takashi Yokochi, Yoshinobu Kimura, Yukihiro Nishiyama

Journal:

Molecular Brain Research

Year:

2003

Language:

english

File:

PDF, 363 KB

english, 2003

31

Intercellular trafficking activity of herpes simplex virus US11 gene product in the mouse brain

Isamu Mori, Tetsuo Koshizuka, Fumi Goshima, Hiroyasu Ito, Naoki Koide, Tomoaki Yoshida, Takashi Yokochi, Yoshinobu Kimura, Yukihiro Nishiyama

Journal:

Molecular Brain Research

Year:

2005

Language:

english

File:

PDF, 436 KB

english, 2005

32

The US3 protein kinase of herpes simplex virus attenuates the activation of the c-Jun N-terminal protein kinase signal transduction pathway in infected piriform cortex neurons of C57BL/6 mice

Isamu Mori, Fumi Goshima, Tetsuo Koshizuka, Naoki Koide, Tsuyoshi Sugiyama, Tomoaki Yoshida, Takashi Yokochi, Yoshinobu Kimura, Yukihiro Nishiyama

Journal:

Neuroscience Letters

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

33

Treatment of solid sarcomas in immunocompetent mice with novel, oncolytic herpes simplex viruses

Saiko Sugiura, Fumi Goshima, Hiroki Takakuwa, Tetsutaro Sata, Tsutomu Nakashima, Yukihiro Nishiyama

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

34

Intercellular trafficking of herpes simplex virus type 2 UL14 deletion mutant proteins

Yohei Yamauchi, Fumi Goshima, Tetsushi Yoshikawa, Naoki Nozawa, Tetsuo Koshizuka, Yukihiro Nishiyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 429 KB

english, 2002

35

US3 protein kinase of herpes simplex virus protects primary afferent neurons from virus-induced apoptosis in ICR mice

Shinya Asano, Takashi Honda, Fumi Goshima, Yukihiro Nishiyama, Yasuo Sugiura

Journal:

Neuroscience Letters

Year:

2000

Language:

english

File:

PDF, 646 KB

english, 2000

36

Inhibition of influenza a virus replication by a kanamycin derivative

Yoshiyuki Yamada, Kaoru Shimokata, Yoshinari Yamada, Naohiko Yamamoto, Fumi Goshima, Yukihiro Nishiyama

Journal:

Antiviral Research

Year:

1991

Language:

english

File:

PDF, 701 KB

english, 1991

37

Protection Against Pertussis by Acellular Pertussis Vaccines (Takeda, Japan): Household Contact Studies in Kawasaki City, Japan

Tatsuo Kato, Toshiro Goshima, Natsuki Nakajima, Hirofumi Kaku, Yutaka Arimoto, Fumie Hayashi

Journal:

Pediatrics International

Year:

1989

Language:

english

File:

PDF, 284 KB

english, 1989

38

Relation between serum hepatitis C virus-RNA levels and efficacy of interferon-β therapy

YUTAKA MINOHARA, TATSUO KATO, KOUZOU KANKI, TOSHIRO GOSHIMA, NATSUKI NAKAJIMA, HILOHUMI KAKU, YUTAKA ARIMOTO, FUMIE GOSHIMA, HIROAKI ISHIKO

Journal:

Pediatrics International

Year:

1995

Language:

english

File:

PDF, 307 KB

english, 1995

39

Herpes simplex virus induces the marked up-regulation of the zinc finger transcriptional factor INSM1, which modulates the expression and localization of the immediate early protein ICP0

Maki Kamakura, Fumi Goshima, Chenhong Luo, Hiroshi Kimura, Yukihiro Nishiyama

Journal:

Virology Journal

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

40

Oncolytic virotherapy for malignant melanoma with herpes simplex virus type 1 mutant HF10

Watanabe, Daisuke, Goshima, Fumi, Mori, Isamu, Tamada, Yasuhiko, Matsumoto, Yoshinari, Nishiyama, Yukihiro

Journal:

Journal of Dermatological Science

Year:

2008

Language:

english

File:

PDF, 1.94 MB

english, 2008

41

Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch

Yoko Ushijima, Chenhong Luo, Maki Kamakura, Fumi Goshima, Hiroshi Kimura, Yukihiro Nishiyama

Journal:

Virology Journal

Year:

2010

Language:

english

File:

PDF, 2.64 MB

english, 2010

42

Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions

Yoko Ushijima, Fumi Goshima, Hiroshi Kimura, Yukihiro Nishiyama

Journal:

Virology Journal

Year:

2009

Language:

english

File:

PDF, 3.05 MB

english, 2009

43

IL-33 triggers mast cell-mediated innate immunity against lethal herpes simplex virus infection through TNF-α and IL-6

Aoki, Rui, Kawamura, Tatsuyoshi, Goshima, Fumi, Nakae, Susumu, Nakao, Atsuhito, Nishiyama, Yukihiro, Shimada, Shinji

Journal:

Journal of Dermatological Science

Year:

2013

Language:

english

File:

PDF, 61 KB

english, 2013

44

Anti-tumor effects of suberoylanilide hydroxamic acid on Epstein-Barr virus-associated T cell and natural killer cell lymphoma

Siddiquey, Mohammed N.A., Nakagawa, Hikaru, Iwata, Seiko, Kanazawa, Tetsuhiro, Suzuki, Michio, Imadome, Ken-Ichi, Fujiwara, Shigeyoshi, Goshima, Fumi, Murata, Takayuki, Kimura, Hiroshi

Journal:

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

45

Herpes Simplex Virus UL14 Protein Blocks Apoptosis

Yamauchi, Yohei, Daikoku, Tohru, Goshima, Fumi, Nishiyama, Yukihiro

Journal:

Microbiology and Immunology

Year:

2003

Language:

english

File:

PDF, 221 KB

english, 2003

46

Role of latent membrane protein 1 in chronic active Epstein-Barr virus infection-derived T/NK-cell proliferation

Ito, Takuto, Kawazu, Hidetaka, Murata, Takayuki, Iwata, Seiko, Arakawa, Saki, Sato, Yoshitaka, Kuzushima, Kiyotaka, Goshima, Fumi, Kimura, Hiroshi

Journal:

Cancer Medicine

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

47

Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancer

Goshima, Fumi, Esaki, Shinichi, Luo, Chenhong, Kamakura, Maki, Kimura, Hiroshi, Nishiyama, Yukihiro

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 973 KB

english, 2014

48

Mast Cells Play a Key Role in Host Defense against Herpes Simplex Virus Infection through TNF-α and IL-6 Production

Aoki, Rui, Kawamura, Tatsuyoshi, Goshima, Fumi, Ogawa, Youichi, Nakae, Susumu, Nakao, Atsuhito, Moriishi, Kohji, Nishiyama, Yukihiro, Shimada, Shinji

Journal:

The Journal of Investigative Dermatology

Year:

2013

Language:

english

File:

PDF, 1.56 MB

english, 2013

49

Roles of Epstein-Barr virus BGLF3.5 gene and two upstream open reading frames in lytic viral replication in HEK293 cells

Watanabe, Takahiro, Fuse, Kenshiro, Takano, Takahiro, Narita, Yohei, Goshima, Fumi, Kimura, Hiroshi, Murata, Takayuki

Journal:

Year:

2015

Language:

english

File:

PDF, 1.52 MB

english, 2015

50

Auditory and vestibular defects induced by experimental labyrinthitis following herpes simplex virus in mice

Esaki, Shinichi, Goshima, Fumi, Kimura, Hiroshi, Ikeda, Shuta, Katsumi, Sachiyo, Kabaya, Kayoko, Watanabe, Nobuhiro, Hashiba, Motoyuki, Nishiyama, Yukihiro, Murakami, Shingo

Journal:

Acta Oto-Laryngologica

Year:

2011

Language:

english

File:

PDF, 469 KB

english, 2011